| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10871751 | FEBS Letters | 2011 | 10 Pages |
Abstract
⺠miR-375 is epigenetically regulated in human melanomas by hypermethylation. ⺠miR-375 methylation was observed in patient samples derived from primary, regional, distant, and nodular melanomas. ⺠miR-375 ectopic expression inhibited cell growth, invasion, and induced changes in cell morphology in melanoma cells. ⺠Gene expression changes suggest possible roles of miR-375 in cytoskeletal architecture, cell motility and migration.
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Authors
Joseph Mazar, Dan DeBlasio, Subramaniam S. Govindarajan, Shaojie Zhang, Ranjan J. Perera,