Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10871780 | FEBS Letters | 2011 | 9 Pages |
Abstract
⺠Multiple sclerosis is an inflammatory disease leading to demyelination and neurodegeneration. ⺠Mechanisms of innate and adaptive immunity are involved in its pathogenesis. ⺠Mitochondrial injury mediated by reactive oxygen and nitric oxide species is important. ⺠Mechanisms of tissue injury are only partly reflected in models of autoimmune encephalomyelitis.
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Authors
Hans Lassmann, Jack van Horssen,