Article ID Journal Published Year Pages File Type
10871780 FEBS Letters 2011 9 Pages PDF
Abstract
► Multiple sclerosis is an inflammatory disease leading to demyelination and neurodegeneration. ► Mechanisms of innate and adaptive immunity are involved in its pathogenesis. ► Mitochondrial injury mediated by reactive oxygen and nitric oxide species is important. ► Mechanisms of tissue injury are only partly reflected in models of autoimmune encephalomyelitis.
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