| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10871785 | FEBS Letters | 2011 | 6 Pages |
Abstract
⺠An independent association exists between the MHC class I alleles and MS. ⺠Oligoclonal expansion of CD8 T cells occurs within MS lesions and in the CSF. ⺠In transgenic models, mice developed a CD8 T cell-driven EAE. ⺠IL-17-producing CD8 T cells (Tc17) are present in active MS lesions. ⺠Suppressive activity of CD8 Treg correlates with clinical remission of MS.
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Authors
A. Saxena, G. Martin-Blondel, L.T. Mars, R.S. Liblau,