Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10871829 | FEBS Letters | 2010 | 9 Pages |
Abstract
Recent years have placed fission yeast at the forefront of telomere research, as this organism combines a high level of conservation with human telomeres and precise genetic manipulability. Here we highlight some of the latest knowledge of fission yeast telomere maintenance and dysfunction, and illustrate how principles arising from fission yeast research are raising novel questions about telomere plasticity and function in all eukaryotes.
Keywords
MRNMre11/Rad50/Nbs1STEssDNADSBNHEJSSATPEdsDNAATRDDRsingle stranded DNAdouble stranded DNAOB-foldTelomere position effectSingle strand annealingSurvivorTelomereTelomeraseATMRecombinationdouble strand breaknon-homologous end-joiningFission yeastMeiosisHomologous recombinationDNA damage responseCHiPChromatin Immuno-Precipitation
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Authors
Pierre-Marie Dehé, Julia Promisel Cooper,