| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10871890 | FEBS Letters | 2011 | 7 Pages |
Abstract
⺠We investigated the link between osteogenic differentiation and cell migration. ⺠The motility of progenitor cells dramatically changed during differentiation. ⺠A mesenchymal mode of cell migration was promoted by inhibition of ROCK signaling. ⺠Upregulated migration of progenitor cells increased ectopic bone formation in vivo. ⺠Our findings may lead to a new therapeutic strategy for bone formation.
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Authors
Masanori Ichida, Yoshihiro Yui, Kiyoko Yoshioka, Takaaki Tanaka, Toru Wakamatsu, Hideki Yoshikawa, Kazuyuki Itoh,