Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10872015 | FEBS Letters | 2009 | 5 Pages |
Abstract
The Woronin body, a septal pore-associated organelle specific to filamentous ascomycetes, is crucial for preventing cytoplasmic bleeding after hyphal injury. In this study, we show that T1hex-1 transcript and a variant splicing T2hex-1 transcript are up-regulated at alkaline pH. We also show that both hex-1 transcripts are overexpressed in the pregc, nuc-1RIP, and pacCko mutant strains of Neurospora crassa grown under conditions of phosphate shortage at alkaline pH, suggesting that hex-1 transcription may be coregulated by these genes. In addition, we present evidence that N. crassa PacC also has metabolic functions at acidic pH.
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Authors
Juliana Leal, Fábio M. Squina, JanaÃna S. Freitas, Emiliana M. Silva, Carlos J. Ono, Nilce M. Martinez-Rossi, Antonio Rossi,