Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10872046 | FEBS Letters | 2010 | 6 Pages |
Abstract
We have previously demonstrated that RNA interference-mediated suppression of xanthine dehydrogenase (XDH), the rate-limiting enzyme in purine degradation, causes defects in the normal growth and development of Arabidopsis thaliana. Here, we investigated a possible role for XDH in drought tolerance, since this enzyme is also implicated in plant stress responses and acclimatization. When XDH-suppressed lines were subjected to drought stress, plant growth was markedly reduced in conjunction with significantly enhanced cell death and H2O2 accumulation. This drought-hypersensitive phenotype was reversed by pretreatment with exogenous uric acid, the catalytic product of XDH. These results suggest that fully functional purine metabolism plays a role in the Arabidopsis drought acclimatization.
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Life Sciences
Agricultural and Biological Sciences
Plant Science
Authors
Shunsuke Watanabe, Ayami Nakagawa, Shunsuke Izumi, Hiroshi Shimada, Atsushi Sakamoto,