Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10872066 | FEBS Letters | 2011 | 5 Pages |
Abstract
⺠HIV-1 Nef suppresses HSP70-mediated Tat activation. ⺠HSP70 stimulates Tat activation. ⺠The stimulation of Tat by HSP70 is blocked by overexpression of Nef. ⺠The depletion of endogenous HSP70 leads to reduced suppression of LTR-driven transcription by Nef.
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Authors
Ryuichi Sugiyama, Haruki Naganuma, Hironori Nishitsuji, Hiroshi Takaku,