Article ID Journal Published Year Pages File Type
10872076 FEBS Letters 2011 6 Pages PDF
Abstract
► VCP levels are decreased in Alzheimer disease brain. ► VCP knockdown in neurons decreases total soluble tau levels. ► VCP knockdown increases the levels of tau phosphorylated at Ser262/356. ► Inhibition of autophagy increases soluble tau phosphorylated at Ser262/356.
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Life Sciences Agricultural and Biological Sciences Plant Science
Preview
Decreases in valosin-containing protein result in increased levels of tau phosphorylated at Ser262/356
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