| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10872094 | FEBS Letters | 2011 | 6 Pages |
Abstract
⺠In this paper, we investigated the effect of berberine on adiponectin multimerization in 3T3-L1 adipocytes. ⺠Berberine inhibits adiponectin expression, but promotes adiponectin multimerization during differentiation of preadipocytes and in mature adipocytes. ⺠Knockdown of AMPKα1 abolishes the effect of berberine on adiponectin multimerization. ⺠Activation of AMPK by AICAR also promotes adiponectin multimerization. ⺠The AMPK signaling pathway plays a positive role in regulating adiponectin multimerization.
Related Topics
Life Sciences
Agricultural and Biological Sciences
Plant Science
Authors
Yun Li, Pengcheng Wang, Yuan Zhuang, Huan Lin, Yehua Li, Ling Liu, Qinghang Meng, Ting Cui, Jing Liu, Zhen Li,