| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10872100 | FEBS Letters | 2011 | 7 Pages |
Abstract
⺠Analysis of the functions of BRC repeat 4 of BRCA2 between mammalian species. ⺠The V1532I substitution in human BRC4 strengthens its interaction with RAD51. ⺠V1532I interferes with RAD51 oligomerization more than wild-type BRC4. ⺠The V1532F mutant in breast cancer patients reduces interaction with RAD51.
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Authors
Kazuhiko Ochiai, Yasunaga Yoshikawa, Kumiko Yoshimatsu, Toshina Oonuma, Yukiko Tomioka, Eichi Takeda, Jiro Arikawa, Katsumi Mominoki, Toshinori Omi, Kazuyoshi Hashizume, Masami Morimatsu,