| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10872429 | FEBS Letters | 2007 | 6 Pages |
Abstract
Glycolipids of Mycobacterium leprae obtained from armadillo tissue nodules infected with the bacteria were analyzed. Mass spectrometric analysis of the glycolipids indicated the presence of trehalose 6,6â²-dimycolate (TDM) together with trehalose 6-monomycolate (TMM) and phenolic glycolipid-I (PGL-I). The analysis showed that M. leprae-derived TDM and TMM possessed both α- and keto-mycolates centering at C78 in the former and at C81 or 83 in the latter subclasses, respectively. For the first time, MALDI-TOF mass analyses showed the presence of TDM in M. leprae.
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Authors
Masanori Kai, Yukiko Fujita, Yumi Maeda, Noboru Nakata, Shinzo Izumi, Ikuya Yano, Masahiko Makino,