Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10872488 | FEBS Letters | 2008 | 4 Pages |
Abstract
Kinesin-1 is a dimeric motor protein that transports cellular cargo along microtubules by using the energy released from ATP hydrolysis and moving processively in 8-nm steps. Recent novel studies at the single molecular level have provided extensive knowledge on how kinesin-1 converts the free energy of ATP hydrolysis and uses it for “walking” along microtubules. In this review, I have discussed the important topics pertaining to the energetics of kinesin-1 stepping mechanism and the consensus walking model.
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Authors
Kenji Kawaguchi,