Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10873720 | FEBS Letters | 2005 | 7 Pages |
Abstract
Conclusion: Statin-reduced endothelial permeability could be attributed to altered intracellular distribution of PECAM-1 in endothelial cells. We speculate that lovastatin regulates PECAM-1 expression in HUVECs through the mevalonate-GGPP pathway by inhibiting of Rho small GTPase.
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Authors
Heming Wei, Lu Fang, Jie Song, Subroto Chatterjee,