| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10873951 | FEBS Letters | 2005 | 5 Pages |
Abstract
The multiprotein Mediator (Med) complex is an evolutionarily conserved transcriptional regulator that plays important roles in activation and repression of RNA polymerase II transcription. Prior studies identified a set of more than twenty distinct polypeptides that compose the Saccharomyces cerevisiae Mediator. Here we discuss efforts to characterize the subunit composition and associated activities of the mammalian Med complex.
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Authors
Joan Weliky Conaway, Laurence Florens, Shigeo Sato, Chieri Tomomori-Sato, Tari J. Parmely, Tingting Yao, Selene K. Swanson, Charles A.S. Banks, Michael P. Washburn, Ronald C. Conaway,