| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10891251 | Stem Cell Research | 2013 | 13 Pages |
Abstract
⺠Mouse gall bladder cells (GBCs) can be robustly expanded ex vivo. ⺠GBCs can be reprogrammed towards the β-cell fate by transcription factors. ⺠Reprogramming is enhanced by addition of small molecules. ⺠Reprogrammed GBCs can engraft and express insulin in vivo for at least 15 weeks.
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Authors
Raymond D. Hickey, Feorillo Galivo, Jonathan Schug, Michael A. Brehm, Annelise Haft, Yuhan Wang, Eric Benedetti, Guoqiang Gu, Mark A. Magnuson, Leonard D. Shultz, Eric Lagasse, Dale L. Greiner, Klaus H. Kaestner, Markus Grompe,