Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10891279 | Stem Cell Research | 2013 | 12 Pages |
Abstract
Our results indicate that over-expression of LMNA or PG by lentiviral gene delivery leads to defects in chondrogenic differentiation potential partially due to an imbalance in oxidative stress.
Keywords
SDF-1LPLIL-8FABPLMNAADIPOQRT-PCRAggAggrecanMSCsECMDMEMprogerinHGPSGFPDulbecco's modified Eagles mediumROSadiponectinALPAlkaline phosphataseOsteoarthritisOsteocalcinInterleukin 8umbilical cordMesenchymal stem cellsHutchinson–Gilford progeria syndromemanganese superoxide dismutasestromal cell-derived factor 1Lipoprotein lipaseExtracellular matrixreal-time polymerase chain reactionlamin AFatty acid binding proteingreen fluorescent proteinReactive oxygen species
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Authors
Jesús Mateos, Alexandre De la Fuente, Iván Lesende-Rodriguez, Pablo Fernández-Pernas, MarÃa C. Arufe, Francisco J. Blanco,