| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10891305 | Stem Cell Research | 2011 | 9 Pages |
Abstract
⺠FGF signaling appears to be important in hESC self-renewal. ⺠FGF2 lacks a signal sequence as it's released from damaged or dead cells. ⺠We made FGF2 secreted cells, using a lentiviral system tagged FGF4 signal peptide. ⺠Two types of hESC lines proliferated without differentiation on 4SP-hFGF2 STO cells. ⺠4SP-hFGF2 cells may be a simple and economic feeder system for hESCs.
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Authors
Won-Young Lee, Jumi Kim, Chang-Hyun Gil, Jae-Ho Lee, Hyuk Song, Jae-Hwan Kim, Hyung-Min Chung,