Palmitic acid increases apoptosis of neural stem cells via activating c-Jun N-terminal kinase

Article ID	Journal	Published Year	Pages	File Type
10891318	Stem Cell Research	2013	10 Pages	PDF

Abstract

âº Palmitic acid promoted apoptosis of neural stem cells. âº Palmitic acid-induced apoptosis of neural stem cells was dose- and time-dependent. âº JNK was activated in palmitic acid-induced apoptosis of neural stem cells.

Keywords

GFAP p-p38 FFAs MAP2 NSCs DAPI Jnk 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide BSA c-Jun N-terminal kinase ERK1/2 MAPKs MTT p-ERK1/2 p-Jnk bovine serum albumin Stearic acid Free fatty acids TUNEL Neural stem cells Phospho-p38 Palmitic acid Glial fibrillary acidic protein microtubule-associated protein 2 mitogen-activated protein kinases

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biotechnology

Preview

Palmitic acid increases apoptosis of neural stem cells via activating c-Jun N-terminal kinase

Authors

Qiuhuan Yuan, Shidou Zhao, Fuwu Wang, Hui Zhang, Zi-Jiang Chen, Juntao Wang, Zhen Wang, Zhaoxia Du, Eng-Ang Ling, Qian Liu, Aijun Hao,