Article ID Journal Published Year Pages File Type
10891319 Stem Cell Research 2013 10 Pages PDF
Abstract
► HMGA2 is an architectural transcription factor that alters chromatin structure. ► HMGA2 induced a PI3K/AKT/mTOR/p70S6K cascade. ► Overexpression of HMGA2 activated cell cycle related genes. ► Overexpression of HMGA2 inhibited CDK inhibitors. ► Overexpression of HMGA2 enhances proliferation and reduces the SA-β-gal activity.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biotechnology
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