Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10891321 | Stem Cell Research | 2013 | 14 Pages |
Abstract
⺠A new strategy for selection of ESC-derived neuronal progenitors is developed. ⺠Strategy relies on a single endogenous marker and avoids genetic modification. ⺠Enrichment based on PSA-NCAM expression improves neuronal differentiation of mESC. ⺠PSA-NCAM enriched progenitors survive, further differentiate and integrate in vivo. ⺠We report an approach to narrow cellular heterogeneity in neuronal differentiation.
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Authors
Serena Barral, Josephine Ecklebe, Stefan Tomiuk, Marie-Catherine Tiveron, Angélique Desoeuvre, Dominik Eckardt, Harold Cremer, Andreas Bosio,