| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10891363 | Stem Cell Research | 2012 | 14 Pages |
Abstract
⺠Drug screening implicates G-subunit-mediated signalling in hESC self-renewal. ⺠Activation of Gα-q/11 coupled GPCR raises free Ca++ and substitutes for bFGF. ⺠Small molecule modulators of free calcium substitutes for bFGF. ⺠Lysophosphatidic acid treatment results in phosphorylation of Calmodulin and STAT3.
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Authors
Alexander Ermakov, Steve Pells, Paz Freile, Veronika V. Ganeva, Jan Wildenhain, Mark Bradley, Adam Pawson, Robert Millar, Paul A. De Sousa,