Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10891366 | Stem Cell Research | 2012 | 12 Pages |
Abstract
⺠We tested all known putative pancreatic cancer stem cells (PCSC) markers. ⺠Cell surface and intracellular markers showed significant variability among cell lines. ⺠Side population response to confluence, hypoxia, radiation, and gemcitabine was inconsistent among cell lines. ⺠A novel subpopulation of SP/CD44-CD24-CD326+ cells demonstrated increased tumorigenicity over previously reported PCSC.
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Authors
Kshama R. Jaiswal, Hong-Wu Xin, Andrew Anderson, Gordon Wiegand, Bo Kim, Tyler Miller, Danielle Hari, Satyajit Ray, Tomotake Koizumi, Udo Rudloff, Snorri S. Thorgeirsson, Itzhak Avital,