| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10891371 | Stem Cell Research | 2012 | 12 Pages |
Abstract
⺠We developed a novel method for culturing human embryonic stem cells (hESCs). ⺠The new method is based on non-colony type monolayer (NCM) growth of hESCs. ⺠NCM retains chromosomal stability and sustains differentiation potential. ⺠The NCM method was shown to homogenize cellular states and control growth rates. ⺠NCM is suitable for high-throughput screening and drug discovery.
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Authors
Kevin G. Chen, Barbara S. Mallon, Rebecca S. Hamilton, Olga A. Kozhich, Kyeyoon Park, Daniel J. Hoeppner, Pamela G. Robey, Ronald D.G. McKay,