| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10891388 | Stem Cell Research | 2012 | 13 Pages |
Abstract
⺠Glycosaminoglycans (GAG) mimetics induce bone regenerative process in vivo. ⺠They stimulate migration and osteogenic differentiation of mesenchymal stem cell (MSC) in vitro. ⺠These effects are dependant on FGF-2 interactions. ⺠Studies on GAG chemical signature underline the role of sulfate and acetyl groups. ⺠GAG mimetics are an alternative to exogenous growth factor to optimize therapeutic properties of MSC for bone repair.
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Authors
Guilhem Frescaline, Thibault Bouderlique, Minh Bao Huynh, Dulce Papy-Garcia, José Courty, Patricia Albanese,