Article ID Journal Published Year Pages File Type
10891394 Stem Cell Research 2012 12 Pages PDF
Abstract
► Expression of fusion yeast cytosine deaminase increases proliferation of CDy::UPRT-MSCs. ► CDy::UPRT-MSCs are hypersensitive to 5-fluorouracil (5FU). ► Chemosensitivity to chemotherapeutic drugs is increased in CDy::UPRT-MSCs. ► CDy::UPRT-MSCs increase 5FU toxicity in human breast cancer cells.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biotechnology
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Increased proliferation and chemosensitivity of human mesenchymal stromal cells expressing fusion yeast cytosine deaminase
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