Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10891397 | Stem Cell Research | 2012 | 7 Pages |
Abstract
⺠We have demonstrated that hypoxia regulates the cystine glutamate exchanger (System Xc). ⺠Hypoxic preconditioning causes an increase in glutathione dependent on System Xc. ⺠Inhibition of system Xc attenuates hypoxic preconditioning neuroprotection.
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Authors
Brian Sims, Melinda Clarke, Ludwig Francillion, Elijah Kindred, Elana Shuford Hopkins, Harald Sontheimer,