Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10961699 | Journal of Equine Veterinary Science | 2012 | 4 Pages |
Abstract
Equine sarcoids are benign fibroblastic skin tumors affecting equids worldwide. Infection with bovine papillomavirus types 1 and 2 has been implicated as a major fact in the disease development; however, the cellular mechanisms underlying fibroblast transformation are still largely unknown. In the present study, a diagnosis of sarcoid was histologically assessed along with eosinophilic dermatitis. The sarcoid lesion expressed the viral oncoproteins E5 and E2, suggesting a causative role of the virus and its replication. Ribosomal DNA of the nematode Habronema muscae was also revealed in the lesion. This is the first report to describe and discuss an association of cutaneous habronemosis with equine sarcoid.
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Authors
Annunziata PhD, Gennaro BSc, Franco DVM, Vincenzo DVM, PhD, Donato DVM, PhD, Angela DVM, Giuseppe DVM, PhD,