Hydroxyethyl starch 130/0.4 compared with 0.9% NaCl administered to greyhounds with haemorrhagic shock

and clinical relevance The effect of 20 mL kg−1 of HES 130/0.4 on shock, as measured by O2ER, was no different than that of 80 mL kg−1 of 0.9% NaCl in dogs under general anaesthesia. Acidaemia in the NaCl group is likely attributable to hyperchloraemic metabolic acidosis from the larger volume administered.