Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10998798 | Veterinary Anaesthesia and Analgesia | 2012 | 12 Pages |
Abstract
Oral administration of some COX-2 selective NSAIDs causes detectable alterations in platelet function in dogs. As in humans, PFA-100 collagen/ADP cartridges do not reliably detect COX-mediated platelet dysfunction in dogs. Individual assessment of platelet function is advised when administering these drugs prior to surgery, particularly in the presence of other risk factors for bleeding.
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Authors
Kathleen B Mullins, John M Thomason, Kari V Lunsford, Lesya M Pinchuk, Vernon C Langston, Robert W Wills, Ronald M McLaughlin, Andrew J Mackin,