Article ID Journal Published Year Pages File Type
10998927 Veterinary Anaesthesia and Analgesia 2011 8 Pages PDF
Abstract
T1 increased significantly during 20 minutes of uninterrupted TOF stimulation in the absence of NMB, establishing that twitch potentiation occurs in anesthetized dogs. With no time for potentiation, T1 increased during the course of recovery from NMB; this phenomenon introduces a bias in T1 measurements and could affect studies reporting potency and duration of NMB based on T1 or single twitches. TOFR was unaltered by potentiation emphasizing its clinical usefulness for excluding post-operative residual NMB.
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