| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10999022 | Veterinary Anaesthesia and Analgesia | 2010 | 9 Pages |
Abstract
When methadone was administered by the SC route, the half-life was longer, but the individual variation in plasma concentrations was greater compared with IV administration. Increased frequency of whining occurred after administration of methadone and may be a drug effect and not a sign of pain. Cortisol and vasopressin concentrations in plasma may not be suitable for evaluating analgesia after methadone treatment.
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Authors
Carina Ingvast-Larsson, Anja Holgersson, Ulf Bondesson, Anne-Sofie Lagerstedt, Kerstin Olsson,