| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10999036 | Veterinary Anaesthesia and Analgesia | 2008 | 6 Pages |
Abstract
One hundred percent propofol is neither safe nor effective when administered via the IM route; presumably as a result of poor systemic uptake of the hydrophobic drug. Newer, water-soluble propofol formulations may circumvent these pharmacokinetic problems, yet local tissue injury might still be possible if high concentrations of free propofol drug are liberated.
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Authors
Carolyn M DVM, Robert J DVM, PhD, Diplomate ACVA, Michael J DVM, Gary J DVM, PhD, Diplomate ACVP,