Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10999313 | Veterinary Anaesthesia and Analgesia | 2007 | 8 Pages |
Abstract
Etomidate in the commercial drug product is solubilized with propylene glycol, a cosolvent associated with adverse side effects on injection. An aqueous formulation of etomidate has been developed, which utilizes SBE-CD as a solubilizing agent. The data suggest that the SBE-CD etomidate formulation may be a safer IV induction formulation than the commercial etomidate drug product.
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Authors
Michelle P PhD, Hideyuki MD, Yoshiyuki MD, Roger A PhD, Hiroshi MD,