| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 11010774 | Stem Cell Research | 2018 | 5 Pages |
Abstract
Peripheral blood mononuclear cells (PBMC) were collected from a 70-year old Parkinson Disease patient. The PBMCs were reprogrammed with the human OKSM transcription factors using the non-integrating episomal vector system. The transgene-free iPSC showed pluripotency verified by immunocytochemistry for pluripotency markers and differentiated directly toward the 3 germ layers in vitro. Furthermore, the iPSC line showed normal karyotype.
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Authors
Zongbo Zhao, Sunping Ji, Zhige Shi, Hui Liu,