Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
11263960 | Biocatalysis and Agricultural Biotechnology | 2018 | 9 Pages |
Abstract
In the era of post genomics, performing a computational analysis to understand the pharmacogenomic based regulation in Psoriatic Arthritis with respect to the principles of data mining and constructing a regulatory network with respect to the principles of systems biology and analyzing the network with respect to the principles of test statistic remains a challenging task to execute. The challenge was approached by identifying the associated genes of Psoriatic Arthritis from PharmGKB and it was followed by identifying the associated regulators (MicroRNAs and Transcription Factors) from miRTarBase/RegNetworks. Finally the compatibility of miRNA in Regulatory Networks is analyzed by the statistical measure in miRmap.
Related Topics
Life Sciences
Agricultural and Biological Sciences
Agricultural and Biological Sciences (General)
Authors
Harishchander Anandaram, Daniel Alex Anand,