Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1150515 | Journal of Statistical Planning and Inference | 2008 | 10 Pages |
Abstract
In this paper we examine the small sample distribution of the likelihood ratio test in the random effects model which is often recommended for meta-analyses. We find that this distribution depends strongly on the true value of the heterogeneity parameter (between-study variance) of the model, and that the correct p-value may be quite different from its large sample approximation. We recommend that the dependence of the heterogeneity parameter be examined for the data at hand and suggest a (simulation) method for this. Our setup allows for explanatory variables on the study level (meta-regression) and we discuss other possible applications, too. Two data sets are analyzed and two simulation studies are performed for illustration.
Related Topics
Physical Sciences and Engineering
Mathematics
Applied Mathematics
Authors
Helle Sørensen,