Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1253951 | Chinese Chemical Letters | 2016 | 4 Pages |
Abstract
A highly enantioselective allylic substitution reaction of anthrones with aromatic or aliphatic allyl carbonates was realized by using iridium catalyst prepared from [Ir(COD)Cl]2 and BHPphos. Substituted 10-allylanthrones were obtained in excellent yields and with excellent enantioselectivity and regioselectivity (up to 98% yield, 99% ee) under mild conditions.
Graphical abstractIridium-catalyzed asymmetric intermolecular Friedel–Crafts type allylic substitution reaction of anthrones was developed, affording C10 substituted allylanthrones in good to excellent yields, regioselectivity and enantioselectivity.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Zheng-Le Zhao, Qing Gu, Xin-Yan Wu, Shu-Li You,