| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1301253 | Inorganic Chemistry Communications | 2016 | 4 Pages |
•A new fluorescence probe based on naphthalimide has been developed.•The detection limit for Cu2 + was estimated to be 64 ppb.•The sensor has practical application in living cells.
A new fluorescence probe L based on naphthalimide has been synthesized for selective and quantitative detection of Cu2 + in CH3CN:H2O (4:1, v/v) solution. L exhibited a strong green fluorescence. Upon addition of 2 equiv. of Cu2 +, the fluorescence emission shows a steady and smooth decrease until a plateau is reached with a 30-fold quenching of fluorescence intensity. In the presence of Cu2 +, the absorbance peak of L maximum at 466 nm decreased, and a new absorption band at 600 nm appeared. Under the identical conditions, other physiological and environmental important metal ions induced negligible spectroscopic changes. The 1:2 stoichiometry binding mode of L with Cu2 + was supported by the Benesi–Hildebrand analysis and ESI-MS spectra studies. The detection limit for Cu2 + was estimated to be 64 ppb. Fluorescence microscopy experiments showed that L has practical application in living cells.
Graphical abstractA new fluorescence probe based on naphthalimide has been synthesized a fluorescent sensor for the selective and quantitative detection of Cu2 + in aqueous solution, and could be application in living cells.Figure optionsDownload full-size imageDownload as PowerPoint slide
