[P2V3W15O62]9 − cluster based covalent polyoxometalate-organic hybrid: Synthesis, structure, self-assembly and in vitro antioxidant activities

•Synthesized a new [P2V3W15O62]9 − cluster based covalent polyoxometalate-organic hybrid P1.•Crystal structure of P1 has been determined.•P1 self-assembles into spherical assemblies of ~ 200 nm size in acetonitrile:water (3:7; v/v) mixture.•P1 exhibits moderate antioxidant activities under standard in vitro experimental conditions.

A new [P2V3W15O62]9 − cluster based covalent polyoxometalate-organic hybrid (P1) containing a naphthol-amide-Tris derivative has been synthesized and characterized using standard analytical and spectroscopic techniques including single crystal X-ray diffraction analyses. P1 exhibits interesting self-assembly behaviour leading to the generation of ~ 200 nm spherical aggregates in solutions as revealed by DLS and TEM analyses. Standard in vitro experiments revealed that P1 is capable of exhibiting moderate antioxidant properties under standard experimental conditions.

Graphical abstractA new [P2V3W15O62]9– cluster based covalent polyoxometalate-organic hybrid containing a naphthol-amide-Tris derivative has been synthesized and structurally characterized using single crystal XRD technique. The in vitro antioxidant activity and solution self-assembly properties of this hybrid are reported.Figure optionsDownload full-size imageDownload as PowerPoint slide