Fe(III) substituted Wells–Dawson type polyoxometalate: An efficient catalyst for ring opening of epoxides with aromatic amines

Various β-aminoalcohols were prepared by the ring opening reaction of epoxides with aromatic amines in the presence of Fe(III) substituted Wells–Dawson type polyoxometalate, α2-[(n-C4H9)4N]7P2W17FeO61·3H2O, as an efficient catalyst. The reaction was performed under neutral condition at room temperature and afforded the corresponding products in high to excellent yields.

Graphical abstractFe(III) substituted Wells–Dawson type polyoxometalate, α2-[(n-C4H9)4N]7P2W17FeO61·3H2O, can act as a mild, efficient, and convenient catalyst for the ring opening of epoxides with aromatic amines at room temperature in acetonitrile.Figure optionsDownload full-size imageDownload as PowerPoint slideHighlights► The use of α2-[(n-C4H9)4N]7P2W17FeO61·3H2O as catalyst. ► Aminolysis of epoxides by α2-[(n-C4H9)4N]7P2W17FeO61·3H2O ► Catalytic ring-opening of epoxides with aromatic amines ► High to excellent yields for giving the 1,2-aminoalcohols