Systematic synthesis of functional unsymmetric FeZn model complexes for plant purple acid phosphatases

The heterodinuclear complexes [FeZn(L)(CH3CO2)2]+ (L = ICIMP or IPCPMP) are structural models for the dinuclear active sites of plant purple acid phosphatases. They can be systematically synthesized from mononuclear iron complexes and enhance the rate of transesterification of 2-hydroxypropyl p-nitrophenyl phosphate, an assay for the catalytic hydrolysis performed by purple acid phosphatases.

Graphical abstractThe heterodinuclear complexes [FeZn(L)(CH3CO2)2]+ (L = ICIMP, IPCPMP) are structural models for the dinuclear active sites of plant purple acid phosphatases. They can be systematically synthesized from mononuclear iron complexes and are functional models that catalyze the transesterification of 2-hydroxypropyl p-nitrophenyl phosphate.Figure optionsDownload full-size imageDownload as PowerPoint slide