A missing oxidation-state level in the family of polyoxo(azide)octadecavanadate(IV/V) clusters: Synthesis, structure and antitumoural properties of [VIV11VV7O44(N3)]10 − in a sodium containing-3D architecture

•A mixed-valence polyoxo(azide)octadecavanadate(IV/V) cluster has been prepared.•The cluster is part of a sodium-containing three-dimensional architecture.•The V18 cluster shows remarkable inhibition properties on human platelet aggregation.•The V18 cluster exhibits significant antitumoural activity against cancer cell lines.

The missing VIV11VV7 oxidation-state member of the polyoxooctadecavanadate(IV/V) — azide family of inorganic host-guest systems has been incorporated in a NaI-containing 3D architecture; the complex shows remarkable inhibition properties on human platelet aggregation and antitumoural activity against cancer cell lines.

Graphical abstractThe missing [VIV11VV7O44(N3)]10 − member in the [HyV18O44(N3)]z − family of polyoxovanadates has been incorporated into a NaI-containing 3D architecture; the resulting compound has impressive inhibitory properties on human platelet aggregation and strong cytotoxic effects on two types of malignant cell lines.Figure optionsDownload full-size imageDownload as PowerPoint slide