| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1303854 | Inorganic Chemistry Communications | 2013 | 5 Pages |
•Formation of Pt-N bond via solid phase synthesis.•A general synthetic method for Pt(II) oligopyridine peptide conjugates.•Structural characterization of complex [Pt(trpy)(pyridine-4-carboxylic acid)](NO3).
Complexes of the general formulae [Pt(trpy)(cpy)]NO3, where cpy = pyridine-2-carboxylic acid, pyridine-3-carboxylic and pyridine-4-carboxylic acid (1)–(3), have been synthesized and characterized. The molecular structure of (3) has been determined by X-ray single crystal diffraction. The resin-immobilized ligand Lys-Lys-4-CO-py (L) interacts with the [Pt(trpy)H2O](NO3)2 via solid phase synthesis, forming the complex [Pt(trpy)(4-CO-py-Lys1-Lys2CONH2)](NO3)4, which has been characterized by 1H NMR and mass spectrometry.
Graphical abstractMixed ligand Pt(II) complexes with 2,2′:6′,2″ terpyridine and pyridine carboxylic acids have been synthesized and characterized. The resin-immobilized ligand Lys2-Lys1-4-CO-py interacts with [Pt(trpy)(H2O)](NO3)2, forming via solid phase synthesis the complex [Pt(trpy)(4-CO-py-Lys1-Lys2CONH2)](NO3)4.Figure optionsDownload full-size imageDownload as PowerPoint slide
