Synthesis, characterization and kinetics properties of chromium(III) complex [Cr(3-HNA)(en)2]Cl · H2O · CH3OH

The reaction of chromium(III) chloride, 3-hydroxy-2-naphthoic acid (3-HNA) and ethylenediamine (en) led to the formation of complex [Cr(3-HNA)(en)2]Cl · H2O · CH3OH, Bis(ethylenediamine-κ2N,N′)(3-hydroxy-2-naphthoic acid-κ2O,O′) chromium(III) monochloride monohydrate monomethanol. The kinetics of transfer of Cr(III) from the title compound to the low-molecular-mass chelator EDTA and to the iron-binding protein apoovotransferrin (apoOTf) were carried out by means of UV–Visible (UV–Vis) and fluorescence spectra in 0.01 M Hepes at pH 7.4. The second-order rate constants were calculated, respectively. The results show that Cr(III) can be transferred from the complex to apoovotransferrin.

Graphical abstract[Cr(3-HNA)(en)2]Cl · H2O · CH3OH is synthesized. The kinetics of transfer of Cr3+ from the title compound to the low-molecular-mass chelator EDTA and to the iron-binding protein apoovotransferrin (apoOTf) were followed by a combination of UV–Visible (UV–Vis) and fluorescence spectra in 0.01 M Hepes at pH 7.4.Figure optionsDownload full-size imageDownload as PowerPoint slide