| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1306783 | Inorganic Chemistry Communications | 2007 | 5 Pages |
Sulfamethoxazole (SMTZ) reacts with Ph3PAuCl and AgCl in methanol/triethylamine to give [Ph3PAu(SMTZ-1H+)] (SMTZ-1H+ = sulfamethoxazolato anion) (1) and [Ag(SMTZ-1H+)] (2). While the lattice of 1 contains single molecules with linear N–Au–P bonds, compound 2 comprises a two-dimensional polymeric assembly of the deprotonated SMTZ ligand and silver ions, which are coordinated by one oxygen and three nitrogens in a distorted tetrahedral array. The microbiologic activities (Mueller–Hinton broth dilution tests) of 1 and 2 were determined in relation to free sulfamethoxazole.
Graphical abstractSulfamethoxazole reacts with Ph3PAuCl and AgCl to give [Ph3PAu(SMTZ-1H+)] (SMTZ-1H+ = sulfamethoxazolato anion) (1) and [Ag(SMTZ-1H+)] (2). The lattice of 1 contains single molecules with linear N–Au–P bonds. Compound 2 comprises a two-dimensional polymeric assembly of deprotonated SMTZ and silver ions. The microbiologic activities of 1 and 2 were determined related to free sulfamethoxazole.Figure optionsDownload full-size imageDownload as PowerPoint slide
