| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1358568 | Bioorganic & Medicinal Chemistry Letters | 2016 | 6 Pages |
Abstract
4-Methyl-5-pentylbenzene-1,3-diol (MPBD) is a secondary metabolite of SteelyA polyketide synthase, which controls cell aggregation and spore maturation of Dictyostelium discoideum. In this study, chemical synthesis of MPBD and its derivatives was achieved. Structure–activity relationship (SAR) studies for antimicrobial activities against Escherichia coli and Bacillus subtilis were also conducted.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Chihiro Murata, Tetsuhiro Ogura, Shuhei Narita, Anna P. Kondo, Natsumi Iwasaki, Tamao Saito, Toyonobu Usuki,