Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1358895 | Bioorganic & Medicinal Chemistry Letters | 2015 | 4 Pages |
Effect of l-cysteine as the cocatalyst on the oxidation of cyclohexane by tert-butylhydroperoxide (TBHP) catalyzed by manganese tetraphenylporphyrin (MnTPP) has been investigated. The results showed that l-cysteine could moderately improve the catalytic activity of MnTPP and significantly increase the selectivity of cyclohexanol. Different from imidazole and pyridine, the l-cysteine may perform dual roles in the catalytic oxidation of cyclohexane. Besides as the axial ligand for MnTPP, the l-cysteine could also react with cyclohexyl peroxide formed as the intermediate to produce alcohol as the main product.
Graphical abstractIn the oxidation of cyclohexane by MnTPP, l-cysteine could moderately improve the catalytic activity of MnTPP and significantly increase the selectivity of cyclohexanol. The l-cysteine may perform dual roles in the catalytic oxidation.Figure optionsDownload full-size imageDownload as PowerPoint slide