Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1359356 | Bioorganic & Medicinal Chemistry Letters | 2014 | 6 Pages |
Abstract
Recent studies focusing on unveiling the biological agents of Aspongopus chinensis have led to the identification of four new norepinephrine derivatives (1–4), three new sesquiterpenoids (5–7), and one new lactam (8). In addition, twenty-three known compounds have been identified, most of which were isolated from this insect for the first time. Selected members of insect-derived substances were evaluated for their biological activities against renal protection in high-glucose-induced mesangial cells and COX-2 inhibition.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yan-Ni Shi, Zheng-Chao Tu, Xin-Long Wang, Yong-Ming Yan, Ping Fang, Zhi-Li Zuo, Bo Hou, Tong-Hua Yang, Yong-Xian Cheng,