| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1359362 | Bioorganic & Medicinal Chemistry Letters | 2014 | 4 Pages |
Abstract
The identification of the novel and selective GPR3 inverse agonist AF64394, the first small molecule inhibitor of GPR3 receptor function, is described. Structure activity relationships and syntheses based around AF64394 are reported.
Graphical abstractThe identification of the novel and selective GPR3 inverse agonist AF64394, the first small molecule inhibitor of GPR3 receptor function, is described. Structure activity relationships and syntheses based around AF64394 are reported.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Thomas Jensen, Lisbeth Elster, Søren Møller Nielsen, Suresh Babu Poda, Frosty Loechel, Christiane Volbracht, Ib Vestergaard Klewe, Laurent David, Stephen P. Watson,